Bisphosphonate

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Long-Term Effects of Bisphosphonate Therapy

In a March 6, 2017 Scientific Report article, Dr. Ma (Dept. of Mechanical Engineering, Imperial College, London), et al. presented findings from a study that investigated the effects of bisphosphonate therapy on the microstructure and strength of bone. Dr. Ma looked at three cohorts of individuals from a total of 21 bone samples: 1) eight [...]

By |2019-05-13T16:44:38-04:00May 13th, 2018|0 Comments

DX Severe Osteoporosis: Part VIII – Implicate Medicine

This is Part VIII of a multi-part essay about my own personal experience with osteoporosis. I will be taking you through the diagnostic and treatment phases of my care in hopes that it provides you a better understanding of osteoporosis in general, and pearls that you can use to better your own bone health. (Start [...]

By |2019-07-02T10:27:00-04:00November 19th, 2017|0 Comments

DX Severe Osteoporosis: Part VI — Drug Therapy, Fixing Without Healing

This is Part VI of a multi-part essay about my own personal experience with osteoporosis. I will be taking you through the diagnostic and treatment phases of my care in hopes that it provides you a better understanding of osteoporosis in general, and pearls that you can use to better your own bone health.  (Start [...]

By |2019-07-02T10:45:17-04:00October 17th, 2017|0 Comments

Is Prolia the right choice to help reduce fracture risk ???

When faced with fractures from severe osteoporosis, taking a bone specific medication to gain bone density (and hopefully bone strength) can be warranted, at least in the short-term. Prolia (denosumab), or one of the four available bisphosphonate medications on the market, are typically the options given by medical doctors for treatment of osteoporosis. None of [...]

By |2019-05-13T17:04:34-04:00September 3rd, 2017|0 Comments

DX Severe Osteoporosis: Part II — A Burning

"Our lives are a burning. The physical processes that fuel and sustain us--breathing and eating--are kinds of burning. Our passion also is a kind of fire. When our lives are lit by our passions, they give off light and heat. In the end our bodies are consumed, and only the gold is left." R. Keith [...]

By |2019-05-13T17:12:13-04:00August 24th, 2017|0 Comments

Treatment Sequence with Osteoporosis Medications Matters

The effects of medications on bone can be dramatic. Glucocorticoids (e.g. prednisone and dexamethasone) for inflammation, thiazolidinediones (e.g. Avandia and Actos) for type 2 diabetes, and proton pump inhibitors (e.g. Prevacid and Nexium) all can lead to dramatic bone loss. In fact, bone loss can be so profound from drug therapy that it is very [...]

By |2019-05-13T17:25:59-04:00March 14th, 2017|0 Comments

A Crisis in the Treatment of Osteoporosis can be Turned Around with a Paradigm Shift

According to an editorial by Drs. Khosla and Shane in the August 2016 Journal of Bone and Mineral Research, there is A Crisis in the Treatment of Osteoporosis.(1) I totally agree...but my call to action is different. The point of the editorial is that even with all the “remarkable advances in the diagnosis and treatment [...]

By |2019-09-09T09:07:25-04:00September 1st, 2016|0 Comments

Are You Taking Medications That Could Cause Osteoporosis?

Unfortunately, some medications can actually CAUSE disease. In a recent review article published in Therapeutic Advances in Musculoskeletal Diseases, Panday, Gona, and Humphrey discuss common medications that can cause bone loss. The authors emphasize the importance of being aware of this often over-looked, drug-induced, adverse side effect. Why?...Because many doctors (although they know that aging, [...]

By |2019-05-14T22:50:24-04:00November 7th, 2014|0 Comments