N-Acetyl Cysteine Improves Bone Regeneration

Free radicals and pro-inflammatory cytokines can be powerful promoters of the aggressive osteoclastic bone-resorbing activity we often see in osteoporosis. N-acetyl cysteine (NAC) is a very powerful antioxidant that can neutralize these free radicals and limit pro-inflammatory cytokines. Considerable research has demonstrated NAC's ability to limit bone loss via these mechanisms. Now, a new study out [...]

By |2019-02-18T16:08:48-04:00May 31st, 2013|0 Comments

Bile and its role in bone health

Bile fluid is a watered-down slurry of salts, cholesterol, and bilirubin that is produced by the the liver and stored in the gallbladder. When released into the small intestine, bile fluid helps us digest fats, including improving the absorption of fat soluble vitamins such as D and K which are important to bone health. New research [...]

By |2019-04-01T10:14:42-04:00May 26th, 2013|0 Comments

The Brain’s Influence on Aging and Bone

As we age, our body slowly loses function--cell activity weakens, tissue loses strength, organs fail--until a point where biological function can no longer sustain life. But some people age more rapidly than others. Why is this? Genes certainly have a lot to do with how long you will live but is this process coordinated, and [...]

By |2019-04-01T10:13:52-04:00May 24th, 2013|0 Comments

Stem Cell Therapy for Osteoporosis

Still in its infancy but looking promising is stem cell therapy for osteoporosis. California's UC Davis is home to the Institute for Regenerative Cures, a leading player in regenerative medicine. Preliminary research with mice, published in Nature Medicine, demonstrated that bone density and strength could be improved using a molecule called LLP2A-Ale that directs mesenchymal stem cells to [...]

By |2019-02-18T16:08:49-04:00May 19th, 2013|0 Comments

Vitamin K2 MK7 and Healthy Bones

Vitamin K is commonly known as an essential factor in making sure our blood clots, to help wounds heal properly. Vitamin K is also a vital cofactor in the carboxylation (a specific chemical reaction) of osteocalcin, a protein released by osteoblasts during bone formation. Once vitamin K initiates carboxylation, osteocalcin can then help guide calcium [...]

By |2019-02-18T16:08:49-04:00May 18th, 2013|0 Comments

Teriparatide and Denosumab Combo: Two is Better Than One

Just released online by Lancet are the 12-month findings from a study combining two osteoporosis drugs. Researchers found that by combining teriparatide and denosumab, two drugs with different mechanisms, bone density improved more than if either drug was used on its own.Findings: % improvement of bone mineral density after 12 months:Lumbar spine:  teriparatide alone 6.2%, denosumab [...]

By |2019-04-13T10:33:59-04:00May 16th, 2013|0 Comments

Soaking Up the Kudos

I just got an email from a patient that I had worked with about 4 or 5 years ago. Seana is a super elite runner but was diagnosed with low bone density and came to me for help. Her symptoms and a battery of lab tests indicated some problems that we were able to address [...]

By |2019-02-18T16:08:49-04:00May 16th, 2013|0 Comments

Zoledronic Acid: New Research

Medications play an important role in the treatment of chronic diseases, but they need to be used judiciously and wisely. A recent article on zoledronic acid (Reclast and Zometa) -- a bisphosphonate medication used to treat osteoporosis and high blood levels of calcium caused by cancer -- illustrates how a stop-gap method for one diagnosis [...]

By |2019-02-18T16:08:49-04:00May 2nd, 2013|0 Comments